// Macoral® //
Macoral®技术平台
相关研究与专利:
[1] Felipe J. O. Varum, Francisco Veiga, João S. Sousa, Abdul W. Basit. Mucus thickness in the gastrointestinal tract of laboratory animals[J]. Journal of Pharmacy and Pharmacology, 2012, 64(2): 218–227. DOI: 10.1111/j.2042-7158.01399.
[2] Liu Dou, Yang Mai, Christine M. Madla, Mine Orlu, Abdul W. Basit. P-glycoprotein expression in the gastrointestinal tract of male and female rats is influenced differently by food[J]. European Journal of Pharmaceutical Sciences, 2018, 123: 569–575. DOI: 10.1016/j.ejps.2018.08.014.
[3] Yang Mai, Liu Dou, Zhicheng Yao, Christine M. Madla, Francesca K. H. Gavins, Farhan Taherali, Heyue Yin, Mine Orlu, Sudaxshina Murdan, Abdul W. Basit. Quantification of P-Glycoprotein in the Gastrointestinal Tract of Humans and Rodents: Methodology, Gut Region, Sex, and Species Matter[J]. Molecular Pharmaceutics, 2021, 18: 1895–1904. DOI: 10.1021/acs.molpharmaceut.0c00574.
[4] Grace B. Hatton, Christine M. Madla, Sarit C. Rabbie, Abdul W. Basit. All disease begins in the gut: Influence of gastrointestinal disorders and surgery on oral drug performance[J]. International Journal of Pharmaceutics, 2018, 548: 408–422.
[5] Felipe Varum, Ana Cristina Freire, Hala M. Fadda, Roberto Bravo, Abdul W. Basit. A dual pH and microbiota-triggered coating (Phloral™) for fail-safe colonic drug release[J]. International Journal of Pharmaceutics, 2020, 583: 119379.
[6] Vipul Yadav, Aileen House, Silvia Matiz, Laura E. McCoubrey, Kimberly A. Bettano, Leena Bhave, Meiyao Wang, Peter Fan, Siqun Zhou, Janice D. Woodhouse, Eirini Poimenidou, Liu Dou, Abdul W. Basit, Lily Y. Moy, Robert Saklatvala, Laxminarayan G. Hegde, Hongshi Yu. Ileocolonic-Targeted JAK Inhibitor: A Safer and More Effective Treatment for Inflammatory Bowel Disease[J]. Pharmaceutics, 2022, 14(11): 2385.
[7] F. J. O. Varum, G. B. Hatton, A. C. Freire, A. W. Basit. A novel coating concept for ileo-colonic drug targeting: Proof of concept in humans using scintigraphy[J]. European Journal of Pharmaceutics and Biopharmaceutics, 2013, 84(3): 573–577.
[8] Fang Liu, Paloma Moreno, Abdul W. Basit. A novel double-coating approach for improved pH-triggered delivery to the ileo-colonic region of the gastrointestinal tract[J]. European Journal of Pharmaceutics and Biopharmaceutics, 2010, 74(3): 311–315.
[9] Yang Mai, Sudaxshina Murdan, Marwa Awadi, Abdul W. Basit. Establishing an in vitro permeation model to predict the in vivo sex-related influence of PEG 400 on oral drug absorption[J]. International Journal of Pharmaceutics, 2018, 542: 280–287.
[10] Yang Mai, Francisco Afonso-Pereira, Sudaxshina Murdan, Abdul W. Basit. Excipient-mediated alteration in drug bioavailability in the rat depends on the sex of the animal[J]. European Journal of Pharmaceutical Sciences, 2017, 107: 249–255.
[11] Yang Mai, et al. Boosting drug bioavailability in men but not women through the action of an excipient[J]. International Journal of Pharmaceutics, 2020, 587: 119678.
[12] Yang Mai, et al. Sex-specific effects of excipients on oral drug bioavailability[J]. International Journal of Pharmaceutics, 2022, 629: 122365.
[13] 深圳奥礼生物科技有限公司.多肽稳定剂和药物组合物:202310041433.0[P].2023-07-11.